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Research experiments and bioinformatic analyses suggest that serum or synovial fluid ferritin and GPX4 activity, among others (8, 99), might serve as combined diagnostic indicators, but large-scale cohort studies are essential to confirm their specificity and sensitivity (194)
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The mechanisms are the same as what happens in the face: reduced fat support combined with collagen and elastin that needs time and help to catch up
In animal disease models, probucol protected the heart from doxorubicin-induced toxicity (Muldrew and Franks, 2009)
